Anxiety Disorders — Study Material for BAMS Students | Ayurveda | Compilation.

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Understanding Anxiety Disorders — A Complete Guide
01

What Is Anxiety?

Anxiety is a subjective sense of unease, dread or foreboding — an uncomfortable feeling of vague fear or apprehension accompanied by characteristic physical sensations. When anxiety becomes excessive, persistent, or disproportionate to any real danger, it crosses into disorder territory.

"Anxiety is considered normal when it is a realistic reaction to a genuine threat and dissipates once danger passes. It becomes pathological when it exceeds the situation, persists beyond developmental norms, or interferes with daily functioning."

Anxiety disorders share features of excessive fear and related behavioural disturbances. Many develop during childhood and tend to persist without treatment.

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Excessive or Persistent

Lasting beyond a developmentally appropriate period.

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Out of Proportion

Response far exceeds what the situation warrants.

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Impairs Functioning

Interferes with social, occupational, or important daily areas.

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Overestimates Danger

Individuals consistently overestimate risk in situations.

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Million affected in India (2017)
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% Prevalence in adolescents
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% Highest prevalence (age 18–29)
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% Urban vs 13.9% Rural
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Epidemiology

Anxiety disorders typically develop before age 30 and are more common among women, individuals with social challenges, and those with a family history of anxiety or depression.

Who Is Most at Risk?

Women > MenUrban communities Age 18–29Family history Social difficultiesHistory of depression Unemployed / low income
03

Why Does Anxiety Develop?

Multiple converging theories explain the origins of anxiety disorders — from genetic roots to learned behaviour.

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Biological / Genetic

First-degree relatives, twin studies, and family history all implicate hereditary factors. Increased sympathetic activity is noted neuroanatomically.

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Psychoanalytic Theory

Freud: anxiety results when ego defence mechanisms fail to resolve the id–superego conflict. Failed repression leads to neurotic symptoms.

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Cognitive Behaviour Theory

Anxiety stems from faulty cognitions — overestimating danger and underestimating one's own coping ability.

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Behaviour Theory

Anxiety is a conditioned response to an environmental stimulus that generalises over time through social learning.

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Psychosocial Factors

Disturbed attachment, childhood maltreatment, overprotective parenting, stressful life events, and adverse family environment.

04

What Happens in the Brain?

Three primary neurotransmitter systems are implicated in anxiety disorders.

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GABA System

Reduced GABA receptor binding increases nerve-cell excitability. Benzodiazepine receptor reduction is seen in GAD (temporal lobe) and PTSD (cortical).

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Serotonin (5-HT)

Abnormal regulation of serotonin release, reuptake, or receptor responsiveness plays a key role across multiple anxiety disorders.

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Noradrenergic System

The locus coeruleus acts as an alarm centre — releasing norepinephrine in response to perceived threat, producing the anxiety experience.

05

Recognising the Symptoms

Physical Symptoms

Dry mouthPalpitations Restlessness & tremorGI discomfort HeadacheChoking sensation BreathlessnessDilated pupils Muscle tensionChest tightness Difficulty swallowingExcessive thirst

Psychological Symptoms

WithdrawalIrritability InsomniaApathy / Loss of interest Feeling worthless or helpless Inability to concentrate Fear of losing control
06

Types of Anxiety Disorders

DSM-5 classifies the following disorders. Tap any row to expand details.

1Separation Anxiety Disorder

Childhood-onset disorder with excessive fear about separation from parents or attachment figures.

  • Nightmares about separation
  • Physical distress symptoms when separated
  • Refusal to leave attachment figures
  • Repeated temper tantrums
  • Persistent worry about unexpected events causing separation
2Selective Mutism

Failure to speak in certain social situations (e.g. school) despite speaking normally elsewhere.

  • Excessive shyness and social isolation
  • Fear of embarrassment; clinging to caregivers
  • Temper tantrums; lack of social communication
  • Interference with academic performance
3Specific Phobias

Persistent, unrealistic fear of a specific object/situation beyond voluntary control, causing significant distress or impaired functioning.

  • Natural environment — storms, water (Hydrophobia), trees (Dendrophobia)
  • Animals — dogs (Cynophobia), frogs (Batrachophobia), horses (Equinophobia)
  • Medical/Mutilation — needles (Trypanophobia), dentists (Dentophobia), blood (Hemophobia)
  • Situational — enclosed spaces (Claustrophobia), heights (Aerophobia), public speaking (Glossophobia)
4Social Anxiety Disorder

Fear of social situations where the person may be scrutinised, embarrassed, or judged negatively.

  • Strong, persistent fear of interpersonal situations
  • Fear of meeting unfamiliar people or public eating/drinking
  • Fear of public speaking or performance
  • Physical signs: sweating, blushing, rapid heartbeat, trembling, shortness of breath
5Agoraphobia

Fear of places where rapid exit is impossible or help is unavailable — being trapped and helpless.

  • Enclosed spaces (cinemas, elevators, stores)
  • Open spaces (parking lots, bridges)
  • Public transport (bus, train, aeroplane)
  • Crowds or waiting in lines
6Panic Disorder

Recurring, unexpected panic attacks — begin abruptly, peak within ~10 minutes, usually short-lived (<1 hour).

  • Sweating, trembling, palpitations
  • Shortness of breath, chest pain
  • Sensation of choking or impending heart attack
  • Fear of dying; altered sense of reality
7Generalised Anxiety Disorder (GAD)

Chronic, persistent, unrealistic worry interfering with daily activities. More common in women.

Diagnosis: anxiety/worry ≥ 6 months AND 3+ of — tension/restlessness, fatigue, difficulty concentrating, irritability, sleep difficulties.

Risk factors: family history, stress, emotional trauma, unemployment/poverty, drug abuse.

8Post-Traumatic Stress Disorder (PTSD)

Develops after exposure to psychological trauma — natural disasters, war, assault, rape.

FlashbacksNightmaresHypervigilance Emotional numbnessInsomniaDissociation Extreme rageSocial isolationSubstance abuse
9Substance/Medication-Induced Anxiety

Nervousness or panic directly caused by use, abuse, or withdrawal of a substance or medication. Medical conditions such as hyperthyroidism, hypothyroidism, hyperparathyroidism, vitamin B12 deficiency, and pheochromocytoma can also trigger anxiety symptoms.

10Obsessive-Compulsive Disorder (OCD)

Chronic disorder with uncontrollable, recurring obsessions (thoughts/impulses) and compulsions (repetitive behaviours).

Common obsessions: contamination, need for symmetry, forbidden thoughts.

Common compulsions: cleaning, checking, ordering, counting, repeating.

Diagnosis: MRI/CT may show enlarged basal ganglia; PET shows increased glucose metabolism in basal ganglia.

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How Are They Diagnosed?

A multi-pronged approach combining physical examination, structured questioning, validated questionnaires, and laboratory tests.

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Physical Exam

Assess appearance, behaviour, and cooperation. Look for sweaty palms, restlessness, and whether anxiety links to an underlying medical condition.

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Clinical Interview

Detailed questions about symptom intensity, duration, medical history, medications, family history, and daily-life interference.

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Questionnaires

Validated tools such as the GAD-7 or Anxiety Screening Questionnaire-15 (ASQ-15) guide diagnosis.

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Lab & Imaging Tests

Blood/urine tests, thyroid function, EEG, CT scan, ECG, and chest X-ray to rule out physical causes.

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Managing Anxiety Disorders

Treatment is most effective when combining psychological therapies with lifestyle changes. Research shows CBT is more effective than medications long-term.

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Psychoeducation

Understanding the "fight-or-flight" response gives patients control over symptoms.

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Mindfulness

Guides attention back to the present, unhooking from anxiety-provoking thought spirals.

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Correct Breathing

Diaphragmatic breathing counters hyperventilation — belly should move, not chest.

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Relaxation Techniques

Progressive muscle relaxation, abdominal breathing, isometric relaxation exercises.

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Cognitive Therapy (CBT)

Challenges faulty beliefs through rational self-talk, reality testing, and cognitive restructuring.

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Exposure Therapy

Step-by-step confrontation of fears to desensitise. Start with the least threatening fear and work up.

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Dietary Adjustments

Ensure adequate magnesium, vitamin B, and calcium. Avoid caffeine, nicotine, salt, and artificial additives.

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Exercise

Burns stress chemicals and promotes relaxation. Aim for physical activity 3–4 times per week.

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Assertiveness Training

Communicating needs honestly builds self-confidence and reduces anxiety-driven passivity.

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Support Groups

Provide peer understanding, psychoeducation, and social network development.

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Pharmacological Treatments

When needed, medications manage symptoms while psychotherapy takes effect. Always consult a qualified clinician.

First-line

SSRIs

Serotonin Reuptake Inhibitors
Citalopram · Escitalopram · Fluoxetine · Fluvoxamine · Paroxetine · Sertraline
⚠ Nausea, dizziness, sexual difficulties, insomnia. Not habit-forming. Takes 2–6 weeks.
Second-line

SNRIs

Serotonin–Norepinephrine Reuptake Inhibitors
Duloxetine (60–120 mg/day) · Venlafaxine (75–225 mg/day)
⚠ Constipation, dizziness, increased blood pressure, nausea.
Alternative

TCAs

Tricyclic Antidepressants
Amitriptyline · Imipramine · Nortriptyline
⚠ More side effects than SSRIs — dry mouth, constipation, weight gain, sexual problems.
Short-term only

Benzodiazepines

Sedatives / Anxiolytics
Alprazolam · Chlordiazepoxide · Diazepam · Lorazepam
⚠ Addictive. Not recommended beyond 6 months. Memory issues, coordination problems.
Off-label

Beta-Blockers

Norepinephrine Blockers
Atenolol · Propranolol · Labetalol
⚠ Avoid in asthma. May cause depression, tiredness, low blood pressure.
Long-term option

Buspirone

Azapirone Anxiolytic
BuSpar — 7.5–60 mg/day
⚠ Fewer side effects than benzodiazepines. Lower dependence risk. Slower onset.
Rarely prescribed

MAOIs

Monoamine Oxidase Inhibitors
Isocarboxazid · Phenelzine · Tranylcypromine
⚠ Serious side-effect profile — nausea, insomnia, light-headedness, diarrhoea.
10

Chittodvega — The Ayurvedic View

Chittodvega (चित्तोद्वेग) — from Chitta (mind/consciousness) + Udvega (anxiety/agitation) — describes the anxious state of mind. Though not named separately in classical texts, it is described as a precursor to Unmada (psychosis).

"Chittodvega is a manas roga (mental disorder) developing due to vitiation of Vata and Pitta along with Rajas and Tamas."

Nidana (Causes)

Asatmyendriyartha SamyogaPrajnaparadha (intellectual transgressions) Parinama (seasonal changes)Shiro-abhighata (head trauma) Past karma

Lakshana (Symptoms)

Shirashunya (head emptiness)Udvega (agitation) Hridgraha (chest tightness)Bhrama (confusion) Anannabhilasha (loss of appetite)Unmattachittatvam (inability to focus)

Chikitsa (Treatment) — Three Pillars

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Daivavyapashraya

Spiritual healing: mantras, gem therapy, homa (fire offerings), fasting on auspicious days, prostration before deities, pilgrimage.

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Yuktivyapashraya

Rational treatment with diet (milk, ghee) and Panchakarma. Medhya Rasayanas: Guduchi, Brahmi, Ashwagandha, Shankhapushpi, Tulsi, Vacha.

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Satvavajaya

Mind control through Jnana, Vijnana, Dhairya, Smriti, and Samadhi — restraining the mind from harmful thoughts and stress.

Compiled from clinical psychiatry and Ayurvedic literature.
Not a substitute for professional medical advice. Consult a qualified healthcare provider.

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